Cortical Thickness and Functional Networks Modules by Cortical Lobes

Synfire chains and cortical songs: temporal modules of cortical activity.

How can neural activity propagate through cortical networks built with weak, stochastic synapses? We find precise repetitions of spontaneous patterns of synaptic inputs in neocortical neurons in vivo and in vitro. These patterns repeat after minutes, maintaining millisecond accuracy. Calcium imaging of slices reveals reactivation of sequences of cells during the occurrence of repeated intracell...

Cortical thickness in schizophrenia

The current study provides a complete MRI analysis of thickness throughout the cerebral cortical mantle in patients with schizophrenia (SZ) and rigorously screened and matched unaffected relatives and controls and an assessment of its relation to psychopathology and subjective cognitive function. We analyzed 3D-anatomical magnetic resonance imaging data sets, obtained at 3 Tesla, from three dif...

Measuring Cortical Thickness

Introduction The overall goal of this master's project is to study the effect of aging on the thickness of the cerebral cortex. There are three inherent challenges in this project: Creating a coherent definition of cortical thickness. Implementing that definition numerically in the context of real MRI data. Applying the thickness implementation to a real dataset of an aging population, and inte...

Cerebral Cortical Thickness Measurements

Measuring the Cortical Thickness

Besides normal aging, a number of brain diseases are known to reduce the amount of grey matter in the brain. To better understand the nature and progression of these disease processes, quantitative measurements of relevant brain structures, such as the regional cortical thickness, are highly desirable. Starting from high resolution volumetric MR images of the human head, a reliable segmentation...